Sermorelin (GHRH 1-29) Testing & Verification
Get your Sermorelin (GHRH 1-29) independently verified by reversed-phase HPLC-UV. KMD Analytical confirms what the material is, how pure it is, and how much peptide is actually in the vial — measured against a certified reference standard.
What Sermorelin is
Sermorelin is a synthetic 29-amino-acid peptide corresponding to the biologically active N-terminal fragment of human growth hormone-releasing hormone, GHRH(1-29), with a C-terminal amide and a molecular weight near 3,358 g/mol. It is the shortest sequence of GHRH that retains full activity and is typically supplied as a lyophilized acetate salt. Unlike tesamorelin it carries no N-terminal acylation, and unlike CJC-1295 it has no added drug-affinity complex or extra substitutions — so it is easily confused with those longer or modified secretagogues. It is sold on the research-chemical market rather than as an approved drug, so labeled identity and content are not independently guaranteed.
Why get your Sermorelin independently tested
- Identity vs. related secretagogues: sermorelin, tesamorelin, CJC-1295, and full-length GHRH(1-44) all present as similar white powders. Retention-time and UV-spectral matching against a certified sermorelin reference standard confirms you received GHRH(1-29) and not a longer or modified analog.
- Net-peptide content vs. label: lyophilized vials are labeled by fill weight, which includes acetate counter-ions, residual moisture, and bulking agents. A net-peptide assay reports the actual milligrams of sermorelin per vial, independent of total powder weight.
- Oxidation and deamidation on storage: the sequence contains an oxidation-prone methionine and deamidation-prone asparagine/aspartate residues, so mishandled or aged material can accumulate degradation products that appear as extra chromatographic peaks.
- Synthesis-related impurities: assembling a 29-residue chain leaves opportunities for truncated and deletion-sequence by-products. Chromatographic purity as area percent shows whether the main peak dominates or is shadowed by closely related synthesis by-products.
What we measure on Sermorelin
Every sermorelin sample is run by reversed-phase HPLC with UV/diode-array detection at 214 nm against a certified reference standard. We report exactly three things: identity (retention-time and UV-spectral match to the reference), chromatographic purity as the area percent of the main peak relative to detectable related impurities, and net-peptide assay as the milligrams of peptide per vial. Together these confirm what the material is and how much peptide is actually present — not merely the total weight of powder in the vial.
Every result is issued as a certificate of analysis you — or anyone you forward it to — can verify cryptographically. Reporting identity, purity, and milligram content is the point: a vial can be pure and still underfilled, so we report all three. More on purity vs. net-peptide content and how to read a peptide COA.
Our scope — stated plainly
Testing is RP-HPLC-UV against a certified reference standard — an identity, purity, and content analysis, not mass spectrometry, and it does not include sterility, endotoxin, heavy-metal, or residual-solvent testing. Sermorelin reference standards are commercially available, so identity testing does not usually require a sourcing delay. KMD Analytical is an independent laboratory.
KMD is an independent RP-HPLC-UV lab. We do not run LC-MS / mass-spec, sterility, endotoxin, or heavy-metal testing. If your job needs a capability we don't have, we'll say so.
Sermorelin testing — FAQ
Can you tell Sermorelin apart from tesamorelin or CJC-1295?
Yes — that is what identity testing is for. We compare your sample's retention time and UV spectrum to a certified sermorelin reference standard. Because sermorelin is the unmodified GHRH(1-29) fragment, it elutes differently from acylated tesamorelin or the modified CJC-1295, so a reference-matched run confirms which secretagogue you actually have. This is a chromatographic and spectral match, not a mass-spectrometry confirmation.
Does the milligram number printed on my vial mean milligrams of peptide?
Not necessarily. Lyophilized vials are labeled by fill weight, which can include acetate counter-ions, residual moisture, and bulking agents. Our net-peptide assay reports the actual milligrams of sermorelin per vial, so you can compare the real peptide content to what the label claims.
Do you confirm molecular weight or run mass spectrometry?
No. We verify identity by retention-time and UV-spectral match against a certified reference standard using RP-HPLC-UV, not by mass spectrometry, and we do not perform sterility, endotoxin, heavy-metal, or residual-solvent testing.
Other peptides we test
Retatrutide · Cagrilintide · Tesamorelin · BPC-157 · see the full panel.